Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 192
interventional 103
Observational 66
Registry 23

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 26
Device 18
Drug|placebo 18
Procedure 17
Other 14
Biological 2
Device|Other 2
Behavioral|Diagnostic Test|Drug|Other 1
Device|Dietary Supplement 1
Diagnostic Test 1
Dietary Supplement 1
Drug|Other 1
Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 41
Germany 8
France 7
China 5
United Kingdom 5
Norway 4
Canada 3
Denmark 3
NA 3
Japan 2
Switzerland 2
Austria 1
Austria|Germany 1
Austria|Switzerland 1
Bosnia and Herzegovina 1
China|Spain|United States|Australia|Austria|Belgium|Canada|Croatia|Czechia|Denmark|Finland|France|Germany|Hong Kong|India|Italy|Korea, Republic of|Latvia|New Zealand|Norway|Poland|Russian Federation|Serbia|Singapore|Slovenia|Sweden|Switzerland|Turkey|Ukraine 1
Finland 1
Finland|France|Switzerland 1
Hungary 1
India 1
Italy 1
Korea, Republic of 1
Netherlands 1
Norway|Singapore|United States|Canada|China|France|Hong Kong|United Kingdom 1
Spain 1
United States|Australia|Canada 1
United States|Austria|Belgium|Canada|Czechia|Denmark|Finland|France|Germany|Hungary|Israel|Italy|Poland|Spain|Sweden 1
United States|Austria|Germany|Korea, Republic of|Switzerland|United Kingdom 1
United States|Canada 1
United States|Canada|Chile|France|Japan|United Kingdom 1
United States|Canada|Czechia|Finland 1

Sites per Study

Site_count Study_Count
1 76
2 7
3 3
4 2
5 2
6 1
8 1
11 2
15 1
16 1
20 1
23 1
32 1
35 1
67 1
100 1
117 1

Phase

Phase Study_Count
N/A 45
Phase 2 14
Phase 1/Phase 2 11
Phase 3 10
Phase 4 9
Phase 1 7
Phase 2/Phase 3 6
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 21
2 68
3 4
4 5
5 1
NA 4

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 224 3.0000 10.00000 10.00000 12.00000 19.00 203.00 13.0000
1st Qu. 224 40.0000 16.00000 25.50000 28.75000 50.00 345.25 52.0000
Median 224 60.0000 20.00000 42.00000 84.00000 55.00 590.00 100.0000
Mean 224 142.4889 24.14286 66.18182 96.35714 231.50 637.00 164.2222
3rd Qu. 224 150.0000 24.00000 66.50000 97.50000 206.25 950.75 200.0000
Max. 224 1176.0000 59.00000 282.00000 413.00000 955.00 1157.00 447.0000

Trial Group Type

group_type Group_Count
Experimental 78
Active Comparator 60
Placebo Comparator 24
Other 15
No Intervention 13
Sham Comparator 4
NA 4

Intervention Model

intervention_model Study_Count
Parallel Assignment 75
Single Group Assignment 21
Factorial Assignment 3
Sequential Assignment 2
Crossover Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 69
Prevention 16
Diagnostic 6
Basic Science 4
Other 3
Supportive Care 3
NA 2

Observational Studies

Studies by Country

Country Study_Count
United States 20
France 9
Germany 5
NA 5
Switzerland 5
China 3
Denmark 3
Italy 3
Finland 2
Sweden 2
Australia 1
Belgium 1
Czechia 1
Egypt 1
Finland|Switzerland 1
India 1
Norway 1
Russian Federation 1
Singapore 1

Sites per Study

Site_count Study_Count
1 53
2 3
3 3
4 1
5 1
6 1
8 1
9 1
16 1
22 1

Enrollment Metrics

Measure Observational
Min 4.00
1st Qu 30.00
Median 87.50
Mean 16568.79
3rd Qu 233.50
Max 1068318.00

Observation Model

observational_model Study_Count
Cohort 37
Case-Only 12
Case-Control 5
Other 5
Case Control 4
Defined Population, Natural History 1
Family-Based 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 54
Retrospective 9
Cross-Sectional 1
Longitudinal, Prospective 1
Other 1

Registries

Studies by Country

Country Study_Count
NA 5
China 3
Denmark 3
United States 3
Finland 2
France 2
Egypt 1
Germany 1
India 1
Italy 1
Switzerland 1

Sites per Study

Site_count Study_Count
1 18
2 4
9 1

Enrollment Metrics

Measure Registries
Min 14.0
1st Qu 60.0
Median 89.0
Mean 102247.5
3rd Qu 7500.0
Max 2240000.0

Registry Model

observational_model Study_Count
Cohort 16
Case-Only 3
Case Control 2
Other 2

Time Perspective

time_perspective Study_Count
Prospective 19
Other 3
Cross-Sectional 1

Follow-up

target_duration Study_Count
6 Months 5
1 Year 3
5 Years 2
1 Day 1
1 Month 1
10 Days 1
10 Years 1
12 Months 1
15 Years 1
2 Months 1
2 Years 1
21 Days 1
24 Months 1
3 Months 1
6 Years 1
90 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03318783 Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial https://ClinicalTrials.gov/show/NCT03318783 Active, not recruiting Oregon Health and Science University 2021-06-30
NCT03309579 SAHaRA: A Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT03309579 Recruiting Ottawa Hospital Research Institute 2021-07-31
NCT03249207 SC IL-1Ra in SAH - Phase III Trial (SCIL) https://ClinicalTrials.gov/show/NCT03249207 Active, not recruiting University of Manchester 2022-10-31
NCT03209830 Pharmaceutical Treatment of Fatigue After Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03209830 Completed Oslo University Hospital 2019-09-13
NCT03204955 A Low ChloridE hyperTonic Solution for Brain Edema https://ClinicalTrials.gov/show/NCT03204955 Completed Emory University 2018-09-30
NCT03201094 Impact of NMES and HPRO on Recovery After SAH https://ClinicalTrials.gov/show/NCT03201094 Recruiting University of Maryland, Baltimore 2020-01-31
NCT03187405 Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. https://ClinicalTrials.gov/show/NCT03187405 Recruiting University Hospital, Caen 2022-10-31
NCT03153150 Start or STop Anticoagulants Randomised Trial (SoSTART) https://ClinicalTrials.gov/show/NCT03153150 Active, not recruiting University of Edinburgh 2021-02-28
NCT03065231 Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03065231 Recruiting University of California, San Diego 2022-01-01
NCT03028298 Sildenafil for DCI https://ClinicalTrials.gov/show/NCT03028298 Active, not recruiting University of Mississippi Medical Center 2020-12-31
NCT02996266 Impact of Fever Prevention in Brain Injured Patients https://ClinicalTrials.gov/show/NCT02996266 Recruiting C. R. Bard 2020-10-31
NCT02987218 Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery https://ClinicalTrials.gov/show/NCT02987218 Completed Postgraduate Institute of Medical Education and Research 2016-10-31
NCT02872857 Subarachnoid Hemorrhage Recovery And Galantamine https://ClinicalTrials.gov/show/NCT02872857 Completed The University of Texas Health Science Center, Houston 2019-07-20
NCT02872636 Extracorporeal Filtration of Subarachnoid Hemorrhage Via Spinal Catheter https://ClinicalTrials.gov/show/NCT02872636 Completed Minnetronix 2018-04-16
NCT02864940 Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients https://ClinicalTrials.gov/show/NCT02864940 Completed Rush University Medical Center 2018-08-15
NCT02829398 Determinants of Vasospasm and Delayed Ischemic Deficits in Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02829398 Completed University Hospital, Toulouse 2011-10-31
NCT02716532 Bioavailability of Medium Chain Triglycerides (MCTs) in Comatose Patients With Acute Brain Injury (ABI) https://ClinicalTrials.gov/show/NCT02716532 Completed Nestlé 2017-05-17
NCT02675985 Early Intensive Physical Therapy in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02675985 Active, not recruiting University of Colorado, Denver 2020-01-24
NCT02636218 Ketamine Infusion in Neurologic Deficit https://ClinicalTrials.gov/show/NCT02636218 Recruiting St. Michael’s Hospital, Toronto 2020-03-31
NCT02614742 SFX-01 After Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT02614742 Completed Evgen Pharma 2019-09-30
NCT02684812 Ultra-early Tranexamic Acid After Subarachnoid Hemorrhage. https://ClinicalTrials.gov/show/NCT02684812 Active, not recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2019-07-29
NCT02560532 Evaluation of the Efficacy and Safety of Clazosentan in Reversing Cerebral Vasospasm in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02560532 Completed Idorsia Pharmaceuticals Ltd. 2017-05-02
NCT02501434 Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin https://ClinicalTrials.gov/show/NCT02501434 Recruiting University of Louisville 2019-03-31
NCT02483351 Aneurysmal Subarachnoid Hemorrhage: Red Blood Cell Transfusion and Outcome https://ClinicalTrials.gov/show/NCT02483351 Completed Ottawa Hospital Research Institute 2018-01-31
NCT02482883 Evaluation of Transcutaneous Trigeminal Nerve Stimulation for Prevention of Cerebral Vasospasm After Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT02482883 Completed Poitiers University Hospital 2019-02-28
NCT02411266 Preconditioning With Limb Ischemia for Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02411266 Recruiting University of Miami 2022-01-31
NCT02381522 Remote Ischemic Pre-conditioning in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02381522 Active, not recruiting Loma Linda University 2019-12-20
NCT02377167 Early Tracheostomy in Ventilated Stroke Patients 2 https://ClinicalTrials.gov/show/NCT02377167 Recruiting University Hospital Heidelberg 2020-03-31
NCT02350335 Transdermal Nicotine Replacement in Smokers With Acute Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02350335 Completed Oslo University Hospital 2015-12-31
NCT02330094 Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02330094 Completed Mayo Clinic 2017-09-01
NCT02323685 Safety and Effect of SANGUINATEâ„¢ Infusion in Patients at Risk of Delayed Cerebral Ischemia (DCI) Following Subarachnoid Hemorrhage (SAH) https://ClinicalTrials.gov/show/NCT02323685 Completed Prolong Pharmaceuticals 2016-06-30
NCT02275949 Acupuncture for Cerebral Vasospasm After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02275949 Completed Kyung Hee University Hospital at Gangdong 2017-06-30
NCT02172703 Non-invasive Brain Pressure Monitoring After Trauma or Hemorrhage https://ClinicalTrials.gov/show/NCT02172703 Completed Kantonsspital Aarau 2015-07-31
NCT02142166 The Role of Biomarker in Serum, Cerebrospinal Fluid and Parenchyma in the Context of Aneurysmal Subarachnoid Hemorrhage. https://ClinicalTrials.gov/show/NCT02142166 Recruiting RWTH Aachen University 2020-12-31
NCT02064075 The Mortality and Changes in Quality of Life of Patients Suffering From SAH With Different Hydration Strategies https://ClinicalTrials.gov/show/NCT02064075 Completed University of Debrecen 2013-10-31
NCT02056769 CT Perfusion Imaging to Predict Vasospasm in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02056769 Active, not recruiting Nova Scotia Health Authority 2018-06-30
NCT03621397 Online Spanish Cognitive Intervention Program for Spanish-Speaking Latino/Hispanic Subarachnoid Hemorrhage Patients https://ClinicalTrials.gov/show/NCT03621397 Recruiting Doctors Hospital at Renaissance 2022-08-31
NCT01982656 Massage Technique for Pain, Anxiety and Delirium in SAH Patients https://ClinicalTrials.gov/show/NCT01982656 Completed Mayo Clinic 2017-12-31
NCT01832389 Goal Directed Therapy After Aneurysmal Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT01832389 Completed Technische Universität München 2015-11-30
NCT01802762 A New Multi-parameter Neuromonitoring System to Save Patients’ Lives in Stroke and Brain Injury https://ClinicalTrials.gov/show/NCT01802762 Completed NeMoDevices AG 2017-02-28
NCT01801306 A New Minimal-invasive Brain Tissue Probe Applying Near Infrared Spectroscopy https://ClinicalTrials.gov/show/NCT01801306 Completed NeMoDevices AG 2014-02-28
NCT01799525 Hypercapnia to Prevent Secondary Ischemia in SAH https://ClinicalTrials.gov/show/NCT01799525 Completed Wuerzburg University Hospital 2014-02-28
NCT01787123 Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysinâ„¢ in Patients With Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01787123 Completed Kwong Wah Hospital 2019-01-01
NCT01664520 Dexmedetomidine and Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT01664520 Completed Turku University Hospital 2016-11-30
NCT01656317 Rehabilitation of Patients After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01656317 Completed Oslo University Hospital 2014-02-27
NCT01593267 Barrow Ruptured Aneurysm Trial https://ClinicalTrials.gov/show/NCT01593267 Completed St. Joseph’s Hospital and Medical Center, Phoenix 2019-10-25
NCT01447095 Effects of Prostacyclin Infusion on Cerebral Vessels and Metabolism in Patients With Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT01447095 Completed Rigshospitalet, Denmark 2014-06-30
NCT01420978 Cerebrospinal Fluid (CSF) Drainage Study https://ClinicalTrials.gov/show/NCT01420978 Completed Mayo Clinic 2013-02-28
NCT01414894 Intensive Management of Pressure and Volume Expansion in Patients With Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01414894 Completed University of Washington 2012-12-31
NCT04309708 Efficacy and Safety Assessment for a New UV-protected Pump Infusion Line in Intravenous Infusion Therapy https://ClinicalTrials.gov/show/NCT04309708 Completed B. Braun Medical International Trading Company Ltd. 2019-09-06
NCT04269408 A Safety and Efficacy Study of NicaPlant® in Aneurysmal Subarachnoid Haemorrhage Patients Undergoing Aneurysm Clipping https://ClinicalTrials.gov/show/NCT04269408 Recruiting BIT Pharma GmbH 2021-03-31
NCT04148105 Cilostazol and Nimodipine Combined Therapy After Aneurysmal Subarachnoid Hemorrhage (aSAH) https://ClinicalTrials.gov/show/NCT04148105 Recruiting Ascension South East Michigan 2022-10-01
NCT04135456 The Optimal Dose of Mannitol for Intraoperative Brain Relaxation During the Operation of Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04135456 Recruiting Beijing Tiantan Hospital 2021-02-28
NCT04126408 Safety and Efficacy of Non-invasive Vagus Nerve Stimulation in the Treatment of Headache in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04126408 Recruiting Northwell Health 2021-01-30
NCT04094155 Retinal Vessel Analysis (rGA) at the Patient Bed in the Context of Non-traumatic Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT04094155 Recruiting RWTH Aachen University 2021-01-01
NCT04042571 Permanent Cerebral Oxymetry Monitoring for Early Diagnosis and Treatment of Delayed Vasospasm After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04042571 Recruiting University Hospital, Bordeaux 2021-09-01
NCT03987139 Cerebral Autoregulation in Patients With Aneurysmal SubArachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT03987139 Recruiting Rigshospitalet, Denmark 2021-01-01
NCT03948256 Danish RAndomized Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT03948256 Recruiting Rigshospitalet, Denmark 2022-12-31
NCT03874208 Prediction for Coma Recovery With Comaweb https://ClinicalTrials.gov/show/NCT03874208 Recruiting Assistance Publique - Hôpitaux de Paris 2022-03-31
NCT03826875 Poststroke Depression in Hemorrhagic Stroke https://ClinicalTrials.gov/show/NCT03826875 Recruiting University of Washington 2024-02-25
NCT03754335 SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture https://ClinicalTrials.gov/show/NCT03754335 Recruiting University Hospital, Toulouse 2020-06-30
NCT03706768 Degradation of the Glycocalyx in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03706768 Recruiting University of Virginia 2020-05-01
NCT03691727 Induced Suppression of Platelets Activity in Aneurysmal SAH Management (iSPASM) https://ClinicalTrials.gov/show/NCT03691727 Recruiting University of Iowa 2021-07-31
NCT03607825 FILtration of Subarachnoid Hemorrhage Via SpinaL CAtheteR Extension https://ClinicalTrials.gov/show/NCT03607825 Recruiting Minnetronix 2020-12-31
NCT03496545 Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury https://ClinicalTrials.gov/show/NCT03496545 Recruiting University of California, San Francisco 2020-07-01
NCT01261091 Early Tracheostomy in Ventilated Stroke Patients https://ClinicalTrials.gov/show/NCT01261091 Completed Heidelberg University 2011-11-30
NCT01258257 EARLYdrain - Outcome After Early Lumbar CSF-drainage in Aneurysmal SAH https://ClinicalTrials.gov/show/NCT01258257 Completed Charite University, Berlin, Germany 2016-08-31
NCT01206283 A Study Comparing Modified Lund Concept and Cerebral Perfusion Pressure-targeted Therapy in Secondary Brain Ischaemia. https://ClinicalTrials.gov/show/NCT01206283 Completed University of Sarajevo 2008-06-30
NCT01158508 Remote Ischemic Preconditioning in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01158508 Completed University of California, Los Angeles 2014-01-31
NCT01137110 Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After aSAH https://ClinicalTrials.gov/show/NCT01137110 Completed Washington University School of Medicine 2013-01-01
NCT01110239 Preconditioning for Aneurismal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01110239 Completed University of Miami 2010-07-31
NCT01095731 The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01095731 Completed Columbia University 2012-07-31
NCT01077206 High-dose Simvastatin for Aneurysmal Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT01077206 Completed Chinese University of Hong Kong 2013-06-30
NCT01024972 Safety Study of Dantrolene in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01024972 Completed University of Massachusetts, Worcester 2013-07-31
NCT00968227 Effect of Red Blood Cell Transfusion on Brain Metabolism in Patients With Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT00968227 Completed Washington University School of Medicine 2015-08-31
NCT00964548 Safety Study of Dantrolene to Treat Cerebral Vasospasm After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT00964548 Completed University of Massachusetts, Worcester 2009-10-31
NCT00873015 Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm https://ClinicalTrials.gov/show/NCT00873015 Completed Hope Pharmaceuticals 2010-11-30
NCT00842049 Lumbar Drainage in Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT00842049 Completed The Leeds Teaching Hospitals NHS Trust 2010-07-31
NCT00839449 Eicosapentaenoic Acid Cerebral Vasospasm Therapy Study https://ClinicalTrials.gov/show/NCT00839449 Completed Yamaguchi University Hospital 2008-06-30
NCT00830843 Inhalatorial Sedation in Patient With Subarachnoid Hemorrhage (SAH) Versus Conventional Intravenous Sedation https://ClinicalTrials.gov/show/NCT00830843 Completed Azienda Ospedaliera San Gerardo di Monza 2011-07-31
NCT00823485 Clinical Efficacy of In-situ Thrombolysis in Case of Intraventricular Haemorraghia by Aneurysm Rupture https://ClinicalTrials.gov/show/NCT00823485 Completed Centre Hospitalier Universitaire de Nice 2009-12-31
NCT02503527 Efficacy and Safety Study of a Low-carbohydrate Tube Feed in Critically Ill Patients Under Insulin Therapy https://ClinicalTrials.gov/show/NCT02503527 Recruiting Fresenius Kabi 2019-09-30
NCT01516658 HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study https://ClinicalTrials.gov/show/NCT01516658 Completed Kobe City General Hospital 2018-03-31
NCT01893190 Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01893190 Completed Edge Therapeutics Inc 2016-01-31
NCT04007263 A Multiple Ascending Dose Study of Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers https://ClinicalTrials.gov/show/NCT04007263 Completed Neurop Inc. 2019-08-30
NCT03585270 Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain https://ClinicalTrials.gov/show/NCT03585270 Recruiting Idorsia Pharmaceuticals Ltd. 2021-05-31
NCT00766844 Cervical Spinal Cord Stimulation for the Prevention of Cerebral Vasospasm https://ClinicalTrials.gov/show/NCT00766844 Completed University of Illinois at Chicago 2008-11-30
NCT00731627 Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial https://ClinicalTrials.gov/show/NCT00731627 Completed Cambridge University Hospitals NHS Foundation Trust 2013-09-30
NCT00626912 PRET: Patients Prone to Recurrence After Endovascular Treatment https://ClinicalTrials.gov/show/NCT00626912 Completed Centre hospitalier de l’Université de Montréal (CHUM) 2015-10-31
NCT00618436 Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention https://ClinicalTrials.gov/show/NCT00618436 Completed University of Cincinnati 2009-09-30
NCT00585559 Acetaminophen in aSAH to Inhibit Lipid Peroxidation and Cerebral Vasospasm https://ClinicalTrials.gov/show/NCT00585559 Enrolling by invitation Vanderbilt University Medical Center 2020-07-31
NCT00566709 Near Infrared Spectroscopy (NIRS) as Transfusion Indicator in Neurocritical Patients https://ClinicalTrials.gov/show/NCT00566709 Completed Hospitales Universitarios Virgen del Rocío 2009-11-30
NCT00558311 Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical Clipping https://ClinicalTrials.gov/show/NCT00558311 Completed Idorsia Pharmaceuticals Ltd. 2010-06-15
NCT00248690 ICP Versus Intracranial Compliance Guided Management in SAH https://ClinicalTrials.gov/show/NCT00248690 Completed Oslo University Hospital 2009-02-28
NCT00235963 A Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin on Subarachnoid Hemorrhage-Induced Vasospasm https://ClinicalTrials.gov/show/NCT00235963 Completed Brigham and Women’s Hospital 2006-01-31
NCT00199706 HyperHAES Versus Placebo - Effect on Intracranial Pressure in SAH Patients https://ClinicalTrials.gov/show/NCT00199706 Completed Oslo University Hospital NA
NCT00197392 Comparative Infection Rates for the Codman BACTISEAL TM External Ventricular Drainage (EVD) System https://ClinicalTrials.gov/show/NCT00197392 Completed Codman & Shurtleff 2009-12-31
NCT00194441 Cerebral Perfusion Pressure (CPP) Management Information Feedback and Nursing https://ClinicalTrials.gov/show/NCT00194441 Completed University of Washington 2008-09-30
NCT00140010 Erythropoietin Therapy for Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT00140010 Completed University of Cambridge 2007-03-31
NCT00124150 Intravenous Magnesium Sulfate in Aneurysmal Subarachnoid Haemorrhage (IMASH) https://ClinicalTrials.gov/show/NCT00124150 Completed Chinese University of Hong Kong 2008-12-31
NCT00111085 Clazosentan in Preventing the Occurrence of Cerebral Vasospasm Following an Aneurysmal Subarachnoid Hemorrhage (aSAH) https://ClinicalTrials.gov/show/NCT00111085 Completed Idorsia Pharmaceuticals Ltd. 2006-03-30
NCT00795288 Statins and Cerebral Blood Flow in Subarachnoid Hemorrhage (SAH) https://ClinicalTrials.gov/show/NCT00795288 Completed Washington University School of Medicine 2013-02-28
NCT00029133 Hypothermia During Intracranial Aneurysm Surgery Trial https://ClinicalTrials.gov/show/NCT00029133 Completed National Institute of Neurological Disorders and Stroke (NINDS) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03361722 Interest of Tissue Oxygen Pressure (PtiO2) Monitoring to Detect a Vasospasm Post Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03361722 Completed Fondation Ophtalmologique Adolphe de Rothschild 2016-09-15
NCT03344744 miRNA Profile in Aneurysmal Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT03344744 Recruiting Chinese University of Hong Kong 2023-08-30
NCT03314779 Combined Intracerebral and Jugular Bulb Microdialysis https://ClinicalTrials.gov/show/NCT03314779 Completed Odense University Hospital 2018-07-01
NCT03287557 Dysregulated CNS Inflammation After Acute Brain Injury https://ClinicalTrials.gov/show/NCT03287557 Completed University of Kentucky 2019-05-24
NCT03164434 Influence of Drainage on EVD ICP-signal https://ClinicalTrials.gov/show/NCT03164434 Completed Universitaire Ziekenhuizen Leuven 2016-05-31
NCT03148340 Volumetric Integral Phase-shift Spectroscopy for Noninvasive Detection of Hemispheric Bioimpedance Asymmetry in Acute Brain Pathology https://ClinicalTrials.gov/show/NCT03148340 Completed Cerebrotech Medical Systems, Inc. 2018-05-10
NCT03115450 Comparison of Pupilometer and Ultrasound of Optic Nerve Sheath Diameter in Estimating Intracranial Pressure (ICP) https://ClinicalTrials.gov/show/NCT03115450 Recruiting Loma Linda University 2020-05-15
NCT03257904 iNtrAcranial PreSsurE in Intensive Care (ICU) (SynapseICU) https://ClinicalTrials.gov/show/NCT03257904 Completed University of Milano Bicocca 2019-12-31
NCT03032471 Swiss SOS MoCA - DCI Study https://ClinicalTrials.gov/show/NCT03032471 Recruiting Swiss SOS Study Group 2020-07-31
NCT02991157 Noninvasive Assessment of Cerebral Oxygenation and Cardiac Function in Patients With Neurovascular Diseases https://ClinicalTrials.gov/show/NCT02991157 Completed National Institute of Mental Health and Neuro Sciences, India 2018-11-30
NCT02983786 Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor https://ClinicalTrials.gov/show/NCT02983786 Active, not recruiting University of Pennsylvania 2020-09-30
NCT02907879 Contrast Enhanced Ultrasound Imaging for Cerebral Perfusion Measurement in Cerebral Vasospasm After SAH https://ClinicalTrials.gov/show/NCT02907879 Recruiting University Hospital Inselspital, Berne 2020-12-31
NCT02894034 Is the Measured Diameter of the Optic Nerve Sheath by Cerebral Scan in Patients With Early-phase Meningeal Hemorrhage, Due to a Ruptured Aneurysm, a Prognostic 6-month Mortality Factor ? https://ClinicalTrials.gov/show/NCT02894034 Active, not recruiting Centre Hospitalier Universitaire, Amiens 2018-08-31
NCT02880059 Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms https://ClinicalTrials.gov/show/NCT02880059 Recruiting University Hospital, Bonn 2018-06-30
NCT02879175 Patients’ Follow-up After Subarachnoid Haemorrhage Caused by Ruptured Intracranial Aneurysms https://ClinicalTrials.gov/show/NCT02879175 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2021-09-30
NCT02866877 Effects of Augmented Renal Clearance on Pharmacokinetic and Pharmacodynamic Properties of Levetiracetam in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02866877 Recruiting University of Colorado, Denver 2020-08-31
NCT02837354 The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage? https://ClinicalTrials.gov/show/NCT02837354 Completed Groupe Hospitalier Paris Saint Joseph 2015-11-30
NCT02795533 Changes in Physical, Cognitive and Emotional Function 5 and 10 Years After Aneurysmal Subarachnoid Hemorrhage (aSAH) https://ClinicalTrials.gov/show/NCT02795533 Enrolling by invitation Oslo University Hospital 2022-12-31
NCT02684500 Aneurysmal Subarachnoid Hemorrhage and Superior Mesenteric Artery Flow Study https://ClinicalTrials.gov/show/NCT02684500 Completed University of Florida 2016-06-30
NCT02540005 Coagulation Disorders After Aneurysmatic Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT02540005 Completed Tampere University Hospital 2016-06-30
NCT02389634 Identification of Novel Molecular Markers for Vasospasm https://ClinicalTrials.gov/show/NCT02389634 Completed St. Joseph’s Hospital and Medical Center, Phoenix 2019-10-25
NCT02304328 Impact of Herniation on WFNS Grading in Spontaneous Subarachnoid Hemorrhage - a SWISS SOS Observational Trial https://ClinicalTrials.gov/show/NCT02304328 Active, not recruiting University Hospital Inselspital, Berne 2020-06-25
NCT02176174 Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study https://ClinicalTrials.gov/show/NCT02176174 Completed University College, London 2016-08-31
NCT02129010 The Pathogenesis of Terson Syndrome and the Role of CSF Tau / Amyloid-ß 40 and 42 in Patients With Aneurysmatic Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02129010 Completed Cantonal Hospital of St. Gallen 2016-02-29
NCT02073890 Neurological Outcome in Patients of Traumatic Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT02073890 Completed Macmillan Research Group UK 2013-04-30
NCT01313975 Electrolyte and Fluid Disturbances in Subarachnoid Hemorrhage and Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01313975 Completed University Hospital Inselspital, Berne 2013-01-31
NCT01885507 Mechanical Ventilation in Brain-injured Patients https://ClinicalTrials.gov/show/NCT01885507 Completed Nantes University Hospital 2014-09-30
NCT01799018 Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01799018 Completed State University of New York - Upstate Medical University 2013-06-30
NCT01686763 Endothelin-1 and Methabolites Concentrations in Mycrodialysis and Cerebrospinal Fluid in Subarachnoid Hemorrhage Patients https://ClinicalTrials.gov/show/NCT01686763 Completed University of Turin, Italy 2008-12-31
NCT01670838 Cardiopulmonary Complication in Aneurysmal Subarachnoid Haemorrhage Patients https://ClinicalTrials.gov/show/NCT01670838 Completed Kuopio University Hospital 2017-08-31
NCT01406457 Monitoring of Delayed Ischemia After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01406457 Completed University of Cincinnati 2012-12-31
NCT01357057 Admission Bio-clinical Score to Predict One-year Outcomes in Coiled Subarachnoid Hemorrhage (SAH) https://ClinicalTrials.gov/show/NCT01357057 Completed Assistance Publique - Hôpitaux de Paris 2011-01-31
NCT04449666 Hippocampal Volume and Memory Functions in Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04449666 Recruiting BDH-Klinik Hessisch Oldendorf 2022-06-15
NCT04415736 Artificial Intelligence in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04415736 Completed Göteborg University 2016-10-31
NCT04329208 Predictive Value of Mean Flow Velocity by TCD in Early Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04329208 Completed Mansoura University Hospital 2019-01-01
NCT04311840 Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study https://ClinicalTrials.gov/show/NCT04311840 Recruiting University Hospital Hradec Kralove 2020-10-31
NCT04265404 Evaluation of qSOFA in Neurosurgical Patients https://ClinicalTrials.gov/show/NCT04265404 Completed Goethe University 2019-08-20
NCT04242784 IMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care https://ClinicalTrials.gov/show/NCT04242784 Active, not recruiting Duke University 2020-12-01
NCT04132115 Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) https://ClinicalTrials.gov/show/NCT04132115 Recruiting Azienda Sanitaria-Universitaria Integrata di Udine 2021-10-31
NCT04063982 Diagnosis-related Outcomes in NeurocriTical Care: Prognostic Estimate by Health-care Providers Versus Risk Scores in Intracerebral and Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04063982 Recruiting University of Leipzig 2025-12-31
NCT04052646 Prehospital Deaths From Spontaneous Subarachnoid Haemorrhages https://ClinicalTrials.gov/show/NCT04052646 Completed Rigshospitalet, Denmark 2020-01-31
NCT04018989 Validation of the FOUR Coma Scale in Russia. https://ClinicalTrials.gov/show/NCT04018989 Recruiting Russian Federation of Anesthesiologists and Reanimatologists 2019-11-30
NCT03980613 Presentation of Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT03980613 Recruiting Rigshospitalet, Denmark 2021-12-31
NCT03815149 Safety and Clinical Effectiveness of Pipelineâ„¢ Shield Devices for Intracranial Aneurysms https://ClinicalTrials.gov/show/NCT03815149 Recruiting Gold Coast Hospital and Health Service 2020-01-30
NCT03801694 Predicting the Development of Myocardial Depression in Acute Neurological Patients https://ClinicalTrials.gov/show/NCT03801694 Recruiting Ohio State University 2019-12-31
NCT03761654 Detection of Myocardial Dysfunction in Non-severe Subarachnoid Hemorrhage (WFNS 1-2) Using Speckle-tracking Echocardiography (STRAIN) https://ClinicalTrials.gov/show/NCT03761654 Recruiting University Hospital, Bordeaux 2020-06-30
NCT03710278 The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat) https://ClinicalTrials.gov/show/NCT03710278 Completed Spartanburg Regional Healthcare System 2019-01-23
NCT03604276 Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03604276 Recruiting Maine Medical Center 2020-12-01
NCT01218191 Acute Neurocardiogenic Injury After Subarachnoid Hemorrhage. https://ClinicalTrials.gov/show/NCT01218191 Completed Direction Centrale du Service de Santé des Armées 2012-02-29
NCT01187420 Bilateral Bispectral Index (BIS) Study https://ClinicalTrials.gov/show/NCT01187420 Completed Icahn School of Medicine at Mount Sinai 2010-10-31
NCT01113645 Impact of Cranioplasty On Cerebral Perfusion https://ClinicalTrials.gov/show/NCT01113645 Completed Assistance Publique - Hôpitaux de Paris 2011-12-31
NCT01101711 Endocrine Dysfunction and Quality of Life After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01101711 Completed Lund University Hospital 2011-02-28
NCT01071382 Epidemiology of Aeromedical Evacuation https://ClinicalTrials.gov/show/NCT01071382 Completed Ruhr University of Bochum 2010-02-28
NCT01038193 Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT01038193 Recruiting Chinese University of Hong Kong 2024-03-31
NCT00962559 Hypopituitarism After Aneurismal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT00962559 Completed Universitätsmedizin Mannheim 2010-02-28
NCT00962546 Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT00962546 Completed Washington University School of Medicine 2011-12-31
NCT00954551 Serum Procalcitonin https://ClinicalTrials.gov/show/NCT00954551 Completed Mayo Clinic 2011-03-31
NCT03894202 Impact of Ultra-Early Intracranial Aneurysm Treatment in SAH https://ClinicalTrials.gov/show/NCT03894202 Recruiting Chinese University of Hong Kong 2022-10-31
NCT00807833 Cerebral Blood Flow (CBF) Disturbances Following Traumatic Brain Injury (TBI) and Subarachnoid Hemorrhage (SAH) https://ClinicalTrials.gov/show/NCT00807833 Completed Azienda Ospedaliera San Gerardo di Monza 2011-07-31
NCT04357626 Determinants of Rehabilitation Outcomes in Survivors of Primary Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT04357626 Completed Tan Tock Seng Hospital 2019-09-15
NCT00787020 Ventriculostomies in SAH: ICP Open or Not? https://ClinicalTrials.gov/show/NCT00787020 Completed Duke University 2009-08-31
NCT00692744 Quality of Life in Elderly After Aneurysmal Subarachnoid Hemorrhage (SAH) https://ClinicalTrials.gov/show/NCT00692744 Completed University Hospital, Rouen 2014-01-31
NCT00614887 Hypothalamo-, Pituitary-, Adrenal Axis Dysfunction in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT00614887 Completed Kuopio University Hospital 2006-11-30
NCT00593268 Evaluation of Cerebral Spinal Fluid and Blood in Patients With Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT00593268 Active, not recruiting Vanderbilt University Medical Center 2015-11-30
NCT00490464 Safety and Efficacy of Nicardipine for the Control of Blood Pressure After SAH https://ClinicalTrials.gov/show/NCT00490464 Completed University of Illinois at Chicago NA
NCT00071565 Familial Intracranial Aneurysm Study II https://ClinicalTrials.gov/show/NCT00071565 Completed University of Cincinnati 2015-05-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03380481 SouthErn China REgisTry for Stroke on Traditional Chinese Medicine https://ClinicalTrials.gov/show/NCT03380481 Recruiting Guangzhou University of Traditional Chinese Medicine 2020-12-31
NCT03822260 Evaluation of Neuroinflamation of SAH https://ClinicalTrials.gov/show/NCT03822260 Active, not recruiting Bezmialem Vakif University 2019-01-31
NCT03318432 Stroke Recovery Initiative - Registry for Stroke Research Studies https://ClinicalTrials.gov/show/NCT03318432 Recruiting University of California, San Francisco 2022-10-27
NCT03281590 Stroke and Cerebrovascular Diseases Registry https://ClinicalTrials.gov/show/NCT03281590 Recruiting University of New Mexico 2021-12-31
NCT03245866 Swiss Study on Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03245866 Recruiting University Hospital, Geneva 2020-12-31
NCT03213392 Enzymatic Evaluation of General Anesthetic Induced Neurotoxicity in Patients With Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03213392 Completed Postgraduate Institute of Medical Education and Research, Chandigarh 2017-07-31
NCT03153748 New Therapeutic System of Ruptured Intracranial Aneurysms Based on Big Data From Chinese Population https://ClinicalTrials.gov/show/NCT03153748 Recruiting Changhai Hospital 2020-12-31
NCT03115905 A Registry Study for Emergency Medical Service of Aneurysmal Subarachnoid Hemorrhage in China https://ClinicalTrials.gov/show/NCT03115905 Recruiting Xuanwu Hospital, Beijing 2020-12-30
NCT02901262 Continuous Quantified EEG in NeuroIntensive Care https://ClinicalTrials.gov/show/NCT02901262 Completed Azienda Ospedaliera San Gerardo di Monza 2017-01-31
NCT02334657 Prospective Study of Long-term Outcome After Non-aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02334657 Completed University Clinic Frankfurt 2014-09-30
NCT02320539 MicroRNA Diagnostics in Subarachnoid Hemorrhage 2 https://ClinicalTrials.gov/show/NCT02320539 Completed Rigshospitalet, Denmark 2015-05-31
NCT02026596 SpareBrain - Mechanisms and Prevention of Secondary Brain Injury in Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT02026596 Completed Tampere University Hospital 2016-12-31
NCT02081820 Admission HbA1C in Aneurysmal Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT02081820 Completed Heinrich-Heine University, Duesseldorf 2014-12-31
NCT01919775 Amnesia After Surgery for Anterior Communicating Aneurysm： High Resolution Magnetic Resonance (MR) Imaging Findings https://ClinicalTrials.gov/show/NCT01919775 Completed Tohoku University 2013-07-31
NCT01804439 Risk Factors in the Initial Presentation of Specific Cardiovascular Disease Syndromes https://ClinicalTrials.gov/show/NCT01804439 Completed University College, London 2010-03-31
NCT01801800 Cardiac Function in Severe Aneurysmal Subarachnoid Haemorrhage Patients https://ClinicalTrials.gov/show/NCT01801800 Completed Nantes University Hospital 2013-12-31
NCT01791257 MicroRNA Diagnostics in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT01791257 Completed Rigshospitalet, Denmark 2014-01-31
NCT04193124 Prolonged Vasospasm in Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT04193124 Completed Hospital El Cruce 2019-01-31
NCT04189471 Recovery After Cerebral Hemorrhage https://ClinicalTrials.gov/show/NCT04189471 Recruiting University of Maryland, Baltimore 2024-01-01
NCT03786068 Time to Specialized Admission in Case of Severe Brain Haemorrhage. https://ClinicalTrials.gov/show/NCT03786068 Completed Rigshospitalet, Denmark 2019-03-30
NCT03214705 Role of CT Perfusion in Predicting Poor Outcome After Subarachnoid Hemorrhage https://ClinicalTrials.gov/show/NCT03214705 Completed Assiut University 2018-02-01
NCT03985176 Delayed Cerebral Ischaemia and Coagulation Alterations After Aneurysmal Subarachnoid Haemorrhage https://ClinicalTrials.gov/show/NCT03985176 Recruiting Tampere University Hospital 2021-08-31
NCT03517670 Safety of Intravenous Milrinone for the Treatment of Subarachnoid Hemorrhage-induced Vasospasm https://ClinicalTrials.gov/show/NCT03517670 Recruiting Nantes University Hospital 2021-05-30